anti-Laminin B1/Β1 Ab-1, Clone: LT3

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anti-Laminin B1/Β1 Ab-1, Clone: LT3, Thermo Scientific™ Lab Vision™

Rat Monoclonal Antibody
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of a, β, and g chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.

Host Species: Rat

Clone: LT3

Isotype: IgG1/k

Species Reactivity: Human, Pig, Hamster, and Mouse. Others not known.

Epitope: Not determined

Immunogen: Murine EHS laminin preparation

Molecular Weight: ~210kDa

Positive Control: LS174T cells, Normal colon or colon CA

Cellular Localization: Basement membrane

Ab-1 reacts with laminin B chain. It stains most human and murine basement membranes, except for glomerular and arterial ones. Applications: Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting
Recommended Storage: 4°C, Do Not Freeze

200µL; 1mg/mL; Unlabeled; Purified without BSA and azide

Thermo Scientific

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